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Raul G. Cuero PhD. Web Site Oficial

Doctor Raul Cuero holds a PhD degree on Microbiology, from Strathclyde University, UK; a Master of Sciences degree on Plant Pathology from Ohio State University, USA; a Bachelor of Sciences degree on Biology from Heidelberg University, USA, and a Biology degree from Universidad del Valle, Colombia.

He has several scientific inventions and publications in different scientific and technological fields including microbial biotechnology and Synthetic biology.

Currently,  He is Chief Scientific Advisor of Biocapital Holdings Inc. Houston USA. www.biocapitalholdings.com.

Founder and Senior Research Scientist and Mentor of the International Park of Creativity “IPOC”Colombia. which main aim is invention and discovery (www.parquedelacreatividad.org).

He is a former Distinguished Professor and Research Scientist at Prairie View A&M University Campus, which is a member of the Texas A&M University System (1988 – 2012). He was Associate Researcher at USDA laboratory, New Orleans, USA (1987).

He is also an international consultant on Biotechnology and on creative processes for building capacity. He was recognized as the Outstanding Alumni from Heidelberg University, USA (2010). He has received several scientific recognitions including the Hispanic Scientist of the year 2013, USA by the Museum of Sciences and Industry (MOSI) in Tampa, Florida, and he has received several Honorary Doctor Degrees. He has also received the NASA Brief Technology Award for his invention on Removal of toxic metals and radionuclides by Martian Simulant soil, 2007. He is an author of several books on creativity and building human capacity.

Anti-UV Technology Using Synthetic Biology

BioCapital Holdings LLC and NASA’s Johnson Space Center, Houston, Texas

This technology uses extracts produced from yeast transformed with a new anti-UV DNA construct to block ultraviolet (UV) radiation.

The anti-UV DNA construct was prepared using synthetic biology and/or conventional molecular biology. Different genetic sequences, including repair proteins — such as heat shock protein (HSP), energy metabolic proteins, and other up-regulating proteins — and other synthetic gene sequences were used.

This work was done by Raul Cuero Ph.D. of BioCapital Holdings, and David S. McKay, Ph.D. of NASA’s Johnson Space Center

 

The 2D DIGE gel from bake yeast cells transformed with the anti-UV DNA construct and from non-transform cells (control). The gel of the anti-UV DNA construct (bottom) shows higher fluorescence than the gel of the non- transformed cells (top) after exposure to laser detection. The higher fluorescence indicates a higher expression of the regulated proteins produced by the anti-UV DNA construct.

Link: https://www.techbriefs.com/component/content/article/tb/techbriefs/manufacturing-prototyping/28870# 2/4

 

DR. RAUL CUERO RENGIFO HAS RECEIVED A NEW U.S PATENT FOR A INVENTION:

Novel patented Invention using Synthetic Biology:

BIOLOGICAL DEVICES AND METHODS OD USE THEREOF FOR THE STUDY AND CONTROL OF ALZHEIMER´S DISEASE

The Patent #  9,890,201 B2 issued by United States Patent and Trademark Office (Feb 13/2018). Described herein are devices and methods for simultaneously expressing amyloid precursor protein and TonB protein. For example, the biological devices and methods described herein increase the production of these two proteins while also reducing the cost, making these proteins more widely accessible for medical research purposes, including for the development of diagnostic test for Alzheimer´s desease.

 

Novel patented Invention using Synthetic Biology:

GLUCOSE SENSORS AND METHODS OF USE THEREOF

The Patent # 9,932,644 B2 issued by United States Patent and Trademark Office (Apr. 03/2018). Described herein are glucose and insulin sensors. The sensors are composed of host cells with DNA specifically designed to produce fluorescence when the cells come into contact with glucose and/or insulin in the sample.

Novel patented Invention using Synthetic Biology:

GLUCOSE AND INSULIN SENSORS AND METHODS OF USE THEREOF

The Patent # 9,683,266 B2 issued by United States Patent and Trademark Office (Jun 20/2017). Described herein are glucose and insulin sensors. The sensors are composed of host cells with DNA specifically designed to produce fluorescence when the cells come into contact with glucose and/or insulin in the sample.

Novel patented Invention using Synthetic Biology:

METHODS AND DEVICES FOR ELECTROMAGNETIC AMPLIFICATION OF NUCLEIC ACIDS

   

THE INVENTION IS A CUTTING EDGE METHOD AND DEVICE FOR ELECTROMAGNETIC AMPLIFICATION OF NUCLEIC ACID.

The Patent # 9,044,729, issued by United States Patent and Trademark Office (June 2/2015) covers the technology to Amplify DNA/RNA Without Heat. This technology provides the following advantages:

  • Higher purity of DNA/RNA.
  • Cost-effective.
  • Amplification Shorter time.
  • Wide range of applications (i.e. pharmaceutical, medicine, agriculture, environmental, forensic science, others)

Dr. Cuero Rengifo and his research team at The International Park of Creativity “IPOC” of Colombia developed this novel technology during a period of six (6) years.

 

Novel patented Invention using Synthetic Biology:

POLYURETHANE BIOFOAMS DERIVED FROM NATURAL PRODUCTS AND METHODS OF MAKING AND USING THEREOF

 

The Patent # 9,868,811 B2 issued by United States Patent and Trademark Office (Jan 16/2018). Described herein are polyurethane compositions based on natural materials, as well as methods for making and using the compositions.

Novel patented Invention using Synthetic Biology:

BIOLOGICAL DEVICES AND METHODS FOR INCREASING THE PRODUCTION OF LYCOPENE FROM PLANTS

 

The Patent # 9,828,609 B2 issued by United States Patent and Trademark Office (Nov. 28, 2017). Described herein are devices and methods for enhancing the physiological properties of plants. For example, the devices and methods described herein increase the production of lycopene, wich has industrial and economic value.

 

Novel patented Invention using Synthetic Biology:

COMPOSITION FOR WATER TREATMENT AND METHODS OF USING THEREOF

The Patent # 9,617,176 B2 issued by United States Patent and Trademark Office (April 11/2017). Described herein are compounds and compositions useful for removing contaminants from water.

Novel patented Invention using Synthetic Biology:

COMPOSITIONS AND METHODS FOR REMOVAL OF TOXIC METALS AND RADIONUCLIDES

The Patent # US 7,309,437 B2 issued by United States Patent and Trademark Office (Dec 18/2007). The present invention relates to compositions and methods for the removal of toxic metals or radionuclides from source materials. Toxic metals may be removed from source materials using a clay, such as attapulgite or highly cationic bentonite, and chitin or chitosan.

 

Novel patented Invention using Synthetic Biology:

EFFECTIVE PLANT BIOCONTROL

The Patent # US 5,830,459 issued by United States Patent and Trademark Office (Nov 3 /1998).  A method for preventing or treating microbial colonization in plants is provided. The method involves application of microorganism such as Bacillus species or Pseudomonas species and a Chitosanase inducer such as Chitosan to the plants.

 

Novel patented Invention using Synthetic Biology:

METHODS FOR INCREASING THE PRODUCTION OF PHENOLIC COMPOUNDS FROM THEOBROMA CACAO

patent-us-9428759-b2

The Patent # 9,428,759 B2 issued by United States Patent and Trademark Office (Aug 30/2016). Described herein are methods for enhancing the production of Phenolic compounds from Theobroma Cacao.

For example, the devices and methods described herein increase the production of Phenolic compounds from Cocoa plants, which has industrial and economic value.

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