METHODS FOR PRODUCING CARBO SUGARS AND APPLICATIONS THEREOF

Link: United States Patent The Patent #11,001,848 B2 issued by United States Patent and Trademark Office (May 11, 2021). Described herein are biological devices and methods for using the same to produce carbo sugars. The biological devices include microbial cells transformed with a DNA construct containing genes for producing a cellulose syn­thase and galactomannan galactosyltransferase. In some instances, the biological devices also include a gene for lipase. Methods for altering the viscosity of petroleum oil using the carbo Read more…

METHODS FOR PRODUCING A POLYACTIVE CARBOHYDRATE AND APPLICATIONS THEREOF

Link: United States Patent The Patent #10,995,353 B2 issued by United States Patent and Trademark Office (May 4, 2021). Described herein are biological devices and methods for using the same to produce a polyactive carbohydrate. The biological devices include microbial cells transformed with a DNA construct containing genes for producing a chitin synthase, a chitosanase, and a chitin deacetylase. In some instances, the biological devices also include a gene for lipase. Methods for using the polyactive carbohydrate are Read more…

BIOLOGICAL DEVICES FOR PRODUCING OXIDIZED ZINC AND APPLICATIONS THEREOF

Link: United States Patent The Patent #10,995,345 B2 issued by United States Patent and Trademark Office (May 4, 2021). Described herein are biological devices and methods for using the same to produce oxidized zinc. The biological devices include microbial cells transformed with a DNA construct containing genes for producing a zinc-related protein, an alkaline phosphatase, and an alcohol dehydro­genase. In some instances, the biological devices also include a gene for lipase. The oxidized zinc compositions produced herein have Read more…

CURRENT INVENTIONS (2020)

Construct DNA sensor and photonicity and detection of Covid-19 virus and/or recognition of its antibody. (Patent pending) Genetically and Nutritionally Modified Microorganism for Production of Light Genetically and Nutritionally Modified Microorganism for Enhancement of Natural Inherent Chlorophyll and Hormones in Plants New construct DNA antiUV (Patent pending) Enhancementof fermentation and metabolite yield, using micro current (Patent pending) Enhancementof cell division and metabolite production, using microcurrent.(Patent pending)

DNA-based glucose sensor and photonicity for early detection of diabetes using saliva

Journal: Diabetes Updates – AOT. Reference: Cuero R and Sanchez L. DNA-based glucose sensor and photonicity for early detection of diabetes using saliva. 2019. Diabetes Updates. OAT 2019 Volume 5: 1-5 Abstract Molecules such as glucose, proteins, and other compounds can be ideal markers for detecting diseases such as diabetes due to their inherent biophotonic characteristics. However, the nature of the source of the sample (e.g., blood, urine, saliva) can introduce interference since some sample components can have Read more…

Construct of DNA glucose sensor yeast plasmid for early detection of diabetes

Journal:Frontiers-Open Access technology – AOT. Reference: Cuero Raúl, J. Navia, D. Agudelo, P.Medina. 18 September 2017. Construct of DNA glucose sensor yeast plasmid for early detection of diabetes. Frontiers in Nanoscience and Nanotechnology OAT 2017, Journal of Integrative Obesity and Diabetes. ISSN: 2056-8827. Volume 3(5): 1-9 Abstract This investigation was aimed at assembling different genetic building blocks to produce a focused DNA sensor to detect proteins related to glucose in blood, in order to diagnose early diabetes Read more…

Molecular and Toxicological characterization of anti-UV Yeast plasmid compound for skin protection

Journal: Frontiers-Open Access technology – AOT. Reference: Cuero, R. Ibarguen H. Molecular and Toxicological characterization of anti-UV Yeast plasmid compound for skin protection, Frontiers in Nanoscience and Nanotechnology OAT 2016, FNN. 1000128 Volume 2(4): 159-164. Abstract In the present investigation, we characterized an anti-ultraviolet (anti-UV) metabolite from a yeast plasmid, including testing the toxicological effects of the metabolite in vivo. The present work included the study of the effect of the anti UV yeast plasmid metabolite on Read more…

Martian soil as a potential source of nanoparticles: Study using martian regolith simulant

Journal: Frontiers-Open Access technology – AOT. Reference: Cuero, R. Martian soil as a potential source of nanoparticles: Study using martian regolith simulant, Frontiers in Nanoscience and Nanotechnology OAT, FNN. Volume 2(2): 91-99. Abstract Nanoparticles are characterized by size (<50 nm) and high energy.  Therefore, the aim of this investigation was to determine the effect of electrical conductivity of the Martian Regolith Simulant (MRS) under UV radiation in relation to production of nanoparticles. Results showed good Read more…

Anti-UV Technology Using Synthetic Biology

BioCapital Holdings LLC and NASA’s Johnson Space Center, Houston, Texas This technology uses extracts produced from yeast transformed with a new anti-UV DNA construct to block ultraviolet (UV) radiation. The anti-UV DNA construct was prepared using synthetic biology and/or conventional molecular biology. Different genetic sequences, including repair proteins — such as heat shock protein (HSP), energy metabolic proteins, and other up-regulating proteins — and other synthetic gene sequences were used. This work was done by Read more…